Antilactoferrin antibodies in autoimmune liver disease
نویسندگان
چکیده
منابع مشابه
Autoimmune liver disease in children.
Autoimmune liver disorders are characterised by an inflammatory liver histology, circulating non-organ specific autoantibodies and increased levels of immunoglobulin G (IgG) in the absence of a known aetiology. They respond to immunosuppressive treatment, which should be instituted as soon as diagnosis is made. Liver disorders with a likely autoimmune pathogenesis include autoimmune hepatitis (...
متن کاملAutoimmune liver disease.
• The diagnosis of autoimmune hepatitis is based on specific immunological, histological and biochemical characteristics after exclusion of other causes of liver disease including viral hepatitis. • Hepatitis E virus infection should be considered in the differential diagnosis of autoimmune hepatitis. • Prednisone, prednisolone, or budesonide are first line treatment options for autoimmune hepa...
متن کاملAutoimmune liver disease
Autoimmunity is regarded as the main mechanism involved in pathogenesis of various liver diseases, such as autoimmune hepatitis (ÁIÇ), primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), autoimmune cholangitis, overlap syndromes AIH-PBC and AIH-PSC and liver dysfunction due to connective tissue diseases. Autoimmune hepatitis is an immune-mediated, autodestructive liver diseas...
متن کاملAntibodies to conformational epitopes of soluble liver antigen define a severe form of autoimmune liver disease.
Prevalence and clinical relevance of antibodies to soluble liver antigen (tRNP((Ser)Sec)/SLA) in autoimmune hepatitis (AIH) have been investigated using partially purified or prokaryotically expressed antigen. The aim of this study was to improve the detection of anti-tRNP((Ser)Sec)/SLA by establishing an immunoassay that was able to identify antibodies directed to conformational epitopes and t...
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References GREEN, K.C. & MARGARETZ, G. (1967) Long-term follow-up of multicentre trial of ethyl-a-p-chlorphenoxyisobutyrate (Clofibrate, 'Atromnid'-S) and Clofibrate Plus Androsterone ('Atromid'). Progress in Biochemical Pharmacology, 2, 378. KATSILAMBROS, BRAATEN, J.B., FERGUSON, D. & BRADLEY, R.F. (1972) Muscular syndrome after clofibrate. New England Journal of Medicine, 286, 1 10. LANGER, T...
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ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 2001
ISSN: 0009-9104
DOI: 10.1046/j.1365-2249.2001.01524.x